What was one of the earliest medical uses for cocaine?

The use of cocaine in medical settings dates back to the late 19th century, and one of its primary medical applications initially was as a local anesthetic. This was due to its ability to block nerve impulses, which made it effective for procedures requiring localized numbing.

Cocaine was specifically employed in surgeries and dental work, where its anesthetic properties were invaluable. While cocaine was explored in various contexts, such as for headaches and intestinal ailments, its primary and most significant contribution to medicine involved its role as an anesthetic agent.

Thus, while the option chosen focuses on depression, it does not reflect the key historical application where cocaine played a pivotal role in revolutionizing pain management in medical procedures. The recognition of cocaine as an effective local anesthetic marks a vital chapter in the use of substances for medical purposes, influencing further research and the development of more modern anesthetics.