What condition occurs when an individual requires more of a substance to achieve the same effect due to repeated use?

When an individual requires increasing amounts of a substance to achieve the same effects that were once attained with smaller doses, this phenomenon is referred to as tolerance. Tolerance is a common response to the repeated use of many substances, as the body begins to adapt to the presence of the drug, leading to diminished effects and prompting the individual to consume larger quantities to experience the desired outcomes.

This process can involve neurochemical adaptations in the brain, where receptor sites for the substance might become less sensitive or where the body may produce more enzymes that metabolize the drug more quickly. Over time, this can contribute to a cycle of increased use and potential substance-related issues, including dependency or addiction. Understanding tolerance is crucial for recognizing the risks associated with substance use and the importance of monitoring consumption to prevent harmful patterns.