How addictive is methadone when injected?

Methadone is classified as a long-acting opioid, and when injected, it has the potential for significant abuse and addiction. The correct understanding of its addictive properties is that methadone can be as addictive as heroin due to its pharmacological similarities. Both methadone and heroin are opioids that bind to the same receptors in the brain, leading to the release of pleasurable chemicals. This effect can create a strong desire to continue using the substance to replicate those feelings, making it equally addictive when misused.

When comparing methadone to other substances mentioned, such as cocaine and alcohol, the addiction potential is often determined by how the drugs interact with the brain's reward system. Cocaine, while highly addictive, works differently and typically does not offer the same level of physical dependence that can develop with heroin and other opioids. Alcohol, while also addictive, typically has a different profile and rate of dependence compared to opioid substances. Thus, understanding that methadone can present similar addictive risks as heroin is key to recognizing the concerns surrounding its misuse, particularly when administered via injection.